For two-factors / time-series data, users have more options Together with PCA and heatmaps for visual explorations. It employs general linear models to accommodate modern epidemiological study, MetaboAnalyst now allows users to visualize and compute associations between phenotypes and metabolomics features with considerations of Orthogonal partial least squares-discriminant analysis (OPLS-DA) clustering - dendrogram, heatmap, K-means,Īnd self organizing map (SOM) as well as supervised classification - random forests and support vector machine (SVM). Multivariate - principal component analysis (PCA), partial least squares-discriminant analysis (PLS-DA) and (and metabolites) (SAM) and empirical Bayesian analysis of microarrays (and metabolites) (EBAM) The objective is to enable high-throughput analysis for both targeted and untargeted metabolomics,Īnd to narrow the gap from raw spectra to biological insights.Ī wide array of commonly used statistical and machine learning methods are available: univariate - fold change, t-test, volcano plot,ĪNOVA, correlation analysis advanced feature selection - significance analysis of microarrays Normalization, statistical analysis, functional analysis, meta-analysis as well as integrative analysis with other The current MetaboAnalyst (V5.0) supports raw MS spectra processing, comprehensive data Over the past decade, MetaboAnalyst has evolved to become the most widely used platform (>300,000 users) in the metabolomicsĬommunity. MetaboAnalyst is a comprehensive platform dedicated for metabolomics data analysis via user-friendly, web-based interface. Upgraded the interactive 3D scatter plot for PCA, PLSDA and sPLSDA visual exploration () įeature enhancement to improve performance and visualization for complex large data based on user feedback from OmicsForum () Įnhanced linear models with covariate adjustments ( Statistical Analysis module) to better support different study designs () Minor bug fixes and feature enhancements based on user feedback from OmicsForum ()
#COMPREHENSIVE META ANALYSIS DOWNLOAD#
OmicsNet for omics signatures (lists), orĪdded a checkbox to allow users to explicitly specify group order in Data Editor () Įnhanced error messages for data upload format check fixed the issue with figure legend in 3D scatter plot () Įnhanced result table download for mummichog and covariate adjustment analysis () For multi-omics integration, use MicrobiomeAnalyst for metabolomics & microbiome data,
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